Best Milk Thistle Supplements (Updated August 2025)

Milk thistle is a popular supplement known for its liver-supporting properties. BuyersReport's experts have broken down the features, & benefits of the top-rated, most effective options so you can make an informed choice – our comprehensive review can help you find the milk thistle supplement for your health needs.

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1
Best Overall
Milk Thistle Nutricost

Milk Thistle

10.0 (3,584 reviews)
  • Premium-grade milk thistle supplement with 250mg per capsule
  • Boasts a 4:1 extract concentration that equals to 1,000mg
  • Vegetarian-friendly formula that supports a healthy liver
  • Tested by independent laboratories accredited by the ISO
  • Proudly made in the USA & is free from gluten or GMOs
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Picked by 127 people today

2
Organic Milk Thistle for Liver Support OmniBiotics

Organic Milk Thistle for Liver Support

9.9 (4,602 reviews)
  • For liver detox & cleanse support, helps neutralize free radicals
  • Contains 50% more milk thistle extract than standard products
  • Utilizes an effective, proprietary seed extraction method for maximum potency
  • Offers a potent 4X concentrated extract, providing 1500mg per serving
  • Certified organic, vegan, non-GMO, lab certified & made in the USA
7% Off CHECK PRICE Amazon logo

Picked by 278 people today

3
Max Strength Organic Milk Thistle 30:1 Seed Extract FarmHaven

Max Strength Organic Milk Thistle 30:1 Seed Extract

9.8 (6,868 reviews)
  • Provides a natural way to support healthy liver function
  • Promotes healthy digestion, helps maintain healthy skin
  • Delivers the equivalent of 11,250mg for improved bioavailability & absorption
  • USDA certified organic, plant-based veggie formula, made in the USA
  • Free of gluten, corn, soy, preservatives & any artificial ingredients
20% Off CHECK PRICE Amazon logo

Picked by 220 people today

4
Ultra Strength Milk Thistle Concentrated Extract aSquared Nutrition

Ultra Strength Milk Thistle Concentrated Extract

9.7 (1,303 reviews)
  • Powerful antioxidant, free radical scavenger & detoxifier
  • Helps with liver toxin removal & overall liver function
  • Promotes a more even skin tone & improved skin health
  • Supports brain health w/antioxidant & anti-inflammatory properties
  • 4:1 concentrated extract equivalent to 1000mg of milk thistle
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Picked by 225 people today

5
Extra Strength Milk Thistle 50:1 Extract Zazzee

Extra Strength Milk Thistle 50:1 Extract

9.6 (1,040 reviews)
  • Helps protect liver cells from toxins & promotes overall liver function
  • Contains 80% Silymarin, known for its antioxidant properties
  • 20,000mg strength, 50:1 extract, maximum strength dosage
  • Manufactured in the USA in a fully certified facility
  • Pure, vegan, all-natural, non-GMO & contaminent free
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Picked by 140 people today

Top Rated Milk Thistle Supplement

1
Best Overall
Milk Thistle Nutricost

Milk Thistle

10.0 (3,584 reviews)
  • Premium-grade milk thistle supplement with 250mg per capsule
  • Boasts a 4:1 extract concentration that equals to 1,000mg
  • Vegetarian-friendly formula that supports a healthy liver
  • Tested by independent laboratories accredited by the ISO
  • Proudly made in the USA & is free from gluten or GMOs
CHECK PRICE Amazon logo

Picked by 127 people today