Best Pet Stain Removers (Updated June 2025)

Pet stains can be a persistent problem for pet owners, but finding the right stain remover can make a world of difference. BuyersReport's experts have broken down the features, & benefits of the top-rated, most effective options so you can make an informed choice – our comprehensive review can help you find the best pet stain remover for your home.

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1
Best Overall
Professional Strength Pet Stain & Odor Eliminator Rocco & Roxie Supply Co.

Professional Strength Pet Stain & Odor Eliminator

9.9 (119,179 reviews)
  • Utilizes natural enzymes to break down strong odors & stains
  • Makes tough stains disappear, eliminates odor permanently
  • Professional-grade formula offers quick, high quality results
  • Suitable for floors, upholstery, artificial grass, laundry & more
  • Environmentally friendly, safe to use around pets & children
20% Off CHECK PRICE Amazon logo

Picked by 199 people today

2
Dog & Cat Urine Destroyer & Stain Remover Angry Orange

Dog & Cat Urine Destroyer & Stain Remover

9.8 (28,714 reviews)
  • Active enzymes work to break down pet stains
  • Leaves a pleasant orange citrus scent behind with every spritz
  • Works on carpet, tile, fabric, floor, turf, concrete & more
  • Powerful pet-friendly formula, made in USA
  • No added sulfates, peroxide, bleach, parabens & phthalates
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Picked by 267 people today

3
Pet Stain & Odor Miracle for Carpet Fabrics & Floors Sunny & Honey

Pet Stain & Odor Miracle for Carpet Fabrics & Floors

9.7 (11,022 reviews)
  • Great solution for quick spot cleaning when you have little accidents
  • Bio-enzymatic formula is biodegradable, non-toxic & scented with essential oils
  • Works on many different surfaces, like rugs, hardwood, concrete, tile, furniture & more
  • Powerful cleaning with spring mint scent, neutralizes odors
  • Non-toxic formula, safe around kids & pets
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Picked by 185 people today

4
Professional Grade Pet Stain & Odor Eliminator Smiling Paws Pets

Professional Grade Pet Stain & Odor Eliminator

9.5 (1,250 reviews)
  • Works on carpets, hardwood, rugs, upholstery, litter boxes, grass, tile & more
  • Enzymes activate on contact, attacking the core of the substance you're wanting to eliminate
  • Safe & harmless for pets, kids & the rest of the household
  • Removes 100% of the stains visible under a black light & also non visible odor
  • Lab tested and fully certified, made in the USA
29% Off CHECK PRICE Amazon logo

Picked by 294 people today

5
Pet Stain & Odor Eliminator for Carpet & Clothing Clean-eez

Pet Stain & Odor Eliminator for Carpet & Clothing

9.4 (878 reviews)
  • Makes tough stains disappear
  • Eliminates odors permanently
  • Powerful pro-biotic & enzyme formula
  • Suitable for carpets, clothes, furniture & more
  • Guaranteed to work, no harmful chemicals
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Picked by 178 people today

Top Rated Pet Stain Remover

1
Best Overall
Professional Strength Pet Stain & Odor Eliminator Rocco & Roxie Supply Co.

Professional Strength Pet Stain & Odor Eliminator

9.9 (119,179 reviews)
  • Utilizes natural enzymes to break down strong odors & stains
  • Makes tough stains disappear, eliminates odor permanently
  • Professional-grade formula offers quick, high quality results
  • Suitable for floors, upholstery, artificial grass, laundry & more
  • Environmentally friendly, safe to use around pets & children
20% Off CHECK PRICE Amazon logo

Picked by 199 people today