Best Pet Stain Removers (Updated October 2025)

Pet stains can be a persistent problem for pet owners, but finding the right stain remover can make a world of difference. BuyersReport's experts have broken down the features, & benefits of the top-rated, most effective options so you can make an informed choice – our comprehensive review can help you find the best pet stain remover for your home.

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1
Best Overall
Extreme Advanced Formula Stain & Odor Eliminator Rocco & Roxie

Extreme Advanced Formula Stain & Odor Eliminator

9.9 (122,186 reviews)
  • Extreme strength bio-enzymatic formula conquers the worst pet messes
  • Dissipates quickly to leave no smells behind, lightly scented with lemon oil
  • Activates on contact, works continuously until completely eliminated
  • Fast acting formula works great on every surface, every time
  • Certified gentle & Safe to use around pets & children, chlorine free
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Picked by 199 people today

2
Professional Strength Pet Stain & Odor Eliminator Rocco & Roxie Supply Co.

Professional Strength Pet Stain & Odor Eliminator

9.8 (122,131 reviews)
  • Utilizes natural enzymes to break down strong odors & stains
  • Makes tough stains disappear, eliminates odor permanently
  • Professional-grade formula offers quick, high quality results
  • Suitable for floors, upholstery, artificial grass, laundry & more
  • Environmentally friendly, safe to use around pets & children
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Picked by 268 people today

3
Pet Stain & Odor Miracle for Carpet Fabrics & Floors Sunny & Honey

Pet Stain & Odor Miracle for Carpet Fabrics & Floors

9.7 (11,073 reviews)
  • Great solution for quick spot cleaning when you have little accidents
  • Bio-enzymatic formula is biodegradable, non-toxic & scented with essential oils
  • Works on many different surfaces, like rugs, hardwood, concrete, tile, furniture & more
  • Powerful cleaning with spring mint scent, neutralizes odors
  • Non-toxic formula, safe around kids & pets
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Picked by 231 people today

4
Enzyme Pet Stain & Odor Destroyer Puracy

Enzyme Pet Stain & Odor Destroyer

9.6 (9,022 reviews)
  • No-rinse formula lifts smelly accidents, keeping fabrics fresh
  • Infused with the crisp, clean & calming scent of cucumber & mint
  • Expertly crafted, thoughtfully designed with you & the planet in mind.
  • Free from sulfates, ammonia or bleach or any harsh chemicals
  • Plant powered formula, hypoallergenic, safe for kids, cruelty free
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Picked by 158 people today

5
Dog & Cat Urine Destroyer & Stain Remover Angry Orange

Dog & Cat Urine Destroyer & Stain Remover

9.6 (29,402 reviews)
  • Active enzymes work to break down pet stains
  • Leaves a pleasant orange citrus scent behind with every spritz
  • Works on carpet, tile, fabric, floor, turf, concrete & more
  • Powerful pet-friendly formula, made in USA
  • No added sulfates, peroxide, bleach, parabens & phthalates
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Picked by 189 people today

Top Rated Pet Stain Remover

1
Best Overall
Extreme Advanced Formula Stain & Odor Eliminator Rocco & Roxie

Extreme Advanced Formula Stain & Odor Eliminator

9.9 (122,186 reviews)
  • Extreme strength bio-enzymatic formula conquers the worst pet messes
  • Dissipates quickly to leave no smells behind, lightly scented with lemon oil
  • Activates on contact, works continuously until completely eliminated
  • Fast acting formula works great on every surface, every time
  • Certified gentle & Safe to use around pets & children, chlorine free
CHECK PRICE Amazon

Picked by 199 people today